Cardiology Update

Abstract

Atherosclerosis causes coronary artery disease, myocardial infarction, stroke, and peripheral vascular disease.¹ Our understanding of pathogenesis of atherosclerosis continues to evolve: multiple factors are involved, including endothelial dysfunction,² dyslipidemia,³ inflammation⁴ and plaque rupture (Figure 1).⁵ This underlies the importance of pleiotropic effects of statins in treating atherosclerosis.