Juvenile Temporal Arteritis Clinically Masquerading as Temporal Artery Pseudoaneurysm

Authors

  • Alan S. Marcus, MD
  • Billie S. Fyfe, MD

Keywords:

juvenile temporal arteritis, angiolymphoid hyperplasia with eosinophilia, Kimura disease, temporal artery, temporal artery pseudoaneurysm

Abstract

Juvenile temporal arteritis (JTA) is a rare and controversial diagnosis. The clinical features include: age younger than 40 years old, temporal nodule with or without pain, no systemic features and no recurrences or systemic symptoms upon follow up.  The histopathologic features include intimal hyperplasia, endothelial hyperplasia, disruption of the internal elastic lamina and a lymphoeosinophilic panarteritis that lacks germinal centers and granulomatous inflammation.  The differential diagnosis consists of angiolymphoid hyperplasia with eosinophilia (ALHE) and Kimura disease.  It is debated whether JTA is a distinct diagnosis or a subset of ALHE or Kimura disease. We report a case of an 18-year-old man with a clinical presentation of temporal artery psuedoaneurysm, but with histopathologic features of JTA.  The patient has not sought further treatment 2.5 years after the original excision. 

[N A J Med Sci. 2013;6(2):95-99.   DOI:  10.7156/najms.2013.0602095]


References

Nesher G, Oren S, Lijovetzky G, Nesher R. Vasculitis of the temporal arteries in the young. Semin. Arthritis Rheum. 2009;39(2):96–107.

Lie JT, Gordon LP, Titus JL. Juvenile temporal arteritis. Biopsy study of four cases. JAMA. 1975;234(5):496–499.

Tomlinson FH, Lie JT, Nienhuis BJ, Konzen KM, Groover RV. Juvenile temporal arteritis revisited. Mayo Clin. Proc. 1994;69(5):445–447.

Lie JT. Bilateral juvenile temporal arteritis. J Rheumatol. 1995;22(4):774–776.

Kolman OK, Spinelli HM, Magro CM. Juvenile temporal arteritis. J Am. Acad. Dermatol. 2010;62(2):308–314.

Kempf W, Haeffner AC, Zepter K, et al. Angiolymphoid hyperplasia with eosinophilia: evidence for a T-cell lymphoproliferative origin. Hum Pathol. 2002;33(10):1023–1029.

Koubaa W, Verdier M, Perez M, Wechsler J. Intra-arterial angiolymphoid hyperplasia with eosinophilia. J Cutan Pathol. 2008;35(5):495–498.

Gonzalez-Cuyar LF, Tavora F, Zhao XF, et al. Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. Diagn Pathol. 2008;3:22.

Altman DA, Griner JM, Lowe L. Angiolymphoid hyperplasia with eosinophilia and nephrotic syndrome. Cutis. 1995;56(6):334–336; quiz 342.

Azizzadeh M, Namazi MR, Dastghaib L, Sari-Aslani F. Angiolymphoid hyperplasia with eosinophilia and nephrotic syndrome. Int J Dermatol. 2005;44(3):242–244.

Kimura Y, Tsutsumi T, Kuroishikawa Y, Kishimoto S. Angiolymphoid hyperplasia with eosinophilia arising from the facial artery. J Laryngol Otol. 2003;117(7):570–573.

Morton K, Robertson AJ, Hadden W. Angiolymphoid hyperplasia with eosinophilia: report of a case arising from the radial artery. Histopathology. 1987;11(9):963–969.

Fukunaga M. Juvenile temporal arteritis associated with Kimura’s disease. APMIS. 2005;113(5):379–384.

Watanabe C, Koga M, Honda Y, Oh-I T. Juvenile temporal arteritis is a manifestation of Kimura disease. Am J Dermatopathol. 2002;24(1):43–49.

Sandelin H, Holmberg J, Lehtonen J, Huusari H, Korpela A. Traumatic pseudoaneurysm of the superficial temporal artery. Duodecim. 2012;128(4):359–363.

Downloads

Published

2013-04-30

How to Cite

Marcus, MD, A. S., & Fyfe, MD, B. S. (2013). Juvenile Temporal Arteritis Clinically Masquerading as Temporal Artery Pseudoaneurysm. North American Journal of Medicine and Science, 6(2). Retrieved from https://www.najms.com/index.php/najms/article/view/183

Issue

Section

Case Report